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What is CoQ10?

Coenzyme Q10 (CoQ10) is a key compound found in all cells in the body. It is a coenzyme, which means it helps enzymes work more effectively.

What is CoQ10?

Coenzyme Q10 (CoQ10) is a key compound found in all cells in the body. It is a coenzyme, which means it helps enzymes work more effectively.

How does CoQ10 work?

CoQ10 is mainly found in the membrane of mitochondria, where it is used to make energy ^[1].

It is also located in cell membranes and lipoproteins – such as LDL and HDL – where it acts as a powerful antioxidant. CoQ10 stabilizes cell membranes and helps cells work properly ^[2].

People mainly use CoQ10 to:

Increase Mitochondrial Function for Improved Cellular Energy Production

Energy-demanding organs in your body such as the brain, heart, kidneys, muscle and liver have the highest levels of CoQ10 all of which contain many mitochondria and use a lot of energy ^[11].

Abnormal mitochondrial function can cause calcium uptake to be increased by cells, free radicals to be excessively produced, and a decrease in antioxidant protection. This can result in low energy in the brain cells and can even cause migraines ^[12].

Increase Exercise Performance

Oxidative stress can affect muscle function, and thus, exercise performance ^[17].

Similarly, abnormal mitochondrial function can reduce muscle energy, making it hard for muscles to contract efficiently and sustain exercise ^[18].

CoQ10 can help exercise performance by decreasing oxidative stress in the cells and improving mitochondrial functions ^[19].

In fact, one study investigated the effects of CoQ10 on physical activity. Those supplementing with 1,200 mg of CoQ10 per day for 60 days showed decreased oxidative stress ^[20].

Furthermore, supplementing with CoQ10 can increase power during exercise and reduce fatigue, both of which can improve exercise performance ^[21].

Improve Brain, Heart & Lung Health

The brain is very susceptible to oxidative damage due to its high fatty acid content and its high demand for oxygen.

It is this oxidative damage that enhances the production of harmful compounds that could affect memory, cognition and physical functions ^[22].

CoQ10 may help reduce these harmful compounds build up in the brain.

CoQ10 (100 – 320 mg/day) improved exercise capacity in patients with heart problems by increasing the ability of the lungs and heart to deliver oxygen to muscles ^[23].

Out of all of your organs, your lungs have the most contact with oxygen, which makes them extremely susceptible to oxidative damage.

Increased oxidative damage in the lungs and poor antioxidant protection, including low levels of CoQ10, make it more likely for lung issues such as asthma and chronic obstructive pulmonary disease (COPD) to occur ^[24].

Furthermore, it has been shown that people suffering from these present lower levels of CoQ10 ^[25].

A study showed that supplementing with CoQ10 helped reduce inflammation in people who had asthma, as well as their need for steroid medications to help treat it ^[26].

Another study showed improvements in performance during exercise in COPD sufferers. This was observed through better tissue oxygenation and heart rate after supplementing with CoQ10 ^[27].

How do you know if you would benefit from taking Co Q10?

Various issues, including nutrient deficiencies, reduce the body’s ability to make CoQ10 or cause CoQ10 to be used up faster than it can be replaced. In these cases, supplementation can be helpful or may even be necessary ^[28].

While it’s not a very common test, you absolutely can do a blood test to see if you have optimal blood levels of Co Enzyme Q10, and thereby you can deduce if you would potentially benefit from supplementing Co Enzyme Q10.

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Scientific References: